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Guotai Junan's annual strategy for innovative drugs in 2025: innovative pharmaceutical companies have accelerated into the harvest period, and the valuation has been at a historical low in the past five years. Guotai Junan said that the centralized purchasing policy has become stable, mature and normalized, and the marginal impact has weakened. Innovative drugs have gained policy inclination in the medical insurance negotiation. In the past two years, the policy has continued to promote pharmaceutical innovation, and the top-level design and local supporting chain support the development of innovative drugs. Commercial insurance is expected to bring new growth momentum to China's pharmaceutical market, and the overall industry trend is upward. At present, the trend of innovative drug industry is improving, the supply continues to accelerate, and a number of domestic innovative drugs are approved soon, which is expected to drive a new round of heavy volume. At the same time, the commercialization has achieved remarkable results and has occupied a dominant position in some sub-sectors. Pharma's performance continued to differentiate, and innovative drugs and just-needed drugs performed well. Biotech commercialization continues to increase, per capita yield continues to increase, the node of turning losses is approaching, and innovation ushers in the harvest period. Horizontal comparison: compared with overseas peers, the overall valuation of domestic innovative pharmaceutical companies is in a historically low range; Vertical comparison: the valuation of SW- pharmaceutical biology and SW- chemical preparations is at a historical low in the past five years, and it is expected that the valuation of subsequent sectors will pick up.Goldman Sachs: I don't agree that gold can't reach $3,000 under a strong dollar. Goldman Sachs said that we don't agree with the view that the price of gold can't rise to $3,000 per ounce by the end of 2025 when the dollar remains strong for a long time. We predict that gold will reach $3,000 per ounce by the end of 2025, and the reduction of interest rate cuts by the Federal Reserve (rather than the strengthening of the US dollar) is the downside risk of this prediction.SpaceX is valued at about $350 billion due to internal stock sales. According to an email sent to employees seen by the media, SpaceX and its investors have agreed to acquire the company's common stock of up to $1.25 billion at a price of $185 per share. This transaction values elon musk's rocket and satellite manufacturer at about $350 billion.

Expert: Central enterprises will continue to recruit in A-shares. On the evening of December 9, Huada Jiutian, a domestic EDA leader, announced that China Electronic Information Industry Group Co., Ltd. will become the actual controller of the company. So far, the number of A-share listed companies "incorporated" by central enterprises reached 10 in 2024. The end of 2024 is an important node for central enterprises to optimize the layout of listed platforms. The Work Plan for Improving the Quality of Listed Companies Controlled by Central Enterprises previously issued by the State-owned Assets Supervision and Administration Commission of the State Council made it clear that the adjustment and revitalization of the listing platform should be basically completed by the end of 2024, and it is supported to revitalize through absorption and merger, asset restructuring and cross-market operation, or to withdraw through free transfer and equity transfer, so as to further focus on the main business and advantageous areas. Looking forward to the next layout rhythm of central enterprises in the capital market, many experts interviewed by reporters believe that the pace of "recruiting" of central enterprises in A shares will continue. In the coming period, the cases of central enterprises strengthening their main business through capital operation and giving play to their strategic support and industrial leading functions will be on the rise. (shanghai securities news)Galaxy Securities: Macro-policies have increased the accumulation of positive factors in bank fundamentals. The china galaxy Securities Research Report said that the macro-policy upgrade has exceeded expectations and supported the growth of bank credit. Bank spreads are still under pressure, but the release of debt cost optimization results is expected to form support. Preventing and resolving the risk orientation in key areas remains unchanged, and the asset quality and risk expectation of banks are expected to benefit. The positive factors in the fundamentals of banking operations have accumulated, and we will continue to be optimistic about the allocation value of the banking sector and maintain the recommended rating. For individual stocks, ICBC, China Construction Bank, Postal Savings Bank, Jiangsu Bank and Changshu Bank are recommended.Galaxy Securities: The 5G+ industrial chain will be developed in a large scale, and the sub-sector prosperity margin will be optimized to improve the quality target. china galaxy Securities said that the demand for communication equipment as the base of the computing infrastructure of the digital economy is expected to usher in high growth, and related sectors may usher in greater opportunities, focusing on the empowerment of related industrial chains by emerging industries such as operators, optical communications, quantum communications and 5G applications. It is suggested to pay attention to: network infrastructure upgrade+telecom operators, optical module leaders, quantum communication leaders, Internet of Things and cutting-edge applications led by central enterprises.

More than 700 listed companies have announced the replacement of the audit institutions in 2024. According to incomplete statistics, since the beginning of this year, the number of listed companies planning to replace the accounting firms in 2024 has exceeded 700. Among them, the number of listed companies that intend to change accounting firms in October and November is 248 and 200 respectively. Looking back at the "exchange tide", three phenomena stand out: First, in order to improve the quality and ability of capital market intermediaries, the supervision of accounting firms by the regulatory authorities has been significantly enhanced. Based on the principle of prudence, listed companies collectively cancel the contract with the "problem institute"; Second, under the heavy penalty, more and more accountants choose to change their firms to practice, while listed companies choose to change their firms instead of accountants; Third, listed companies employ audit institutions through competitive negotiation, public bidding, invitation bidding, etc. In the bidding process, in order to attract more customers and increase the signing rate, the phenomenon of audit institutions reducing prices has increased. (Securities Daily)Huatai Securities: The expected recovery and fundamental stabilization of the real estate market are expected to accelerate under the policy blessing. Huatai Securities Research Report said that on December 9, the Political Bureau of the Central Committee held a meeting, stressing that it would "implement more active and promising macro policies" and pointed out that it would "stabilize the property market and stock market". Since the end of September, continuous favorable policies have supported fundamental improvement. The central government reiterated its support for real estate at key meetings, which means that there may be more room for policy support next year, and a more relaxed environment is expected to consolidate this improvement trend. The expected repair and fundamental stabilization of the real estate market are expected to accelerate under the blessing of policies. In the follow-up, we should still pay attention to the sustainability of market volume and price recovery and the progress of macro-support policies, purchasing and storage, urban village reconstruction and other policies. Before confirming the bottom of the market, we are more optimistic about housing enterprises with more resources and stable operation in core cities; At the same time, property management companies with resilient performance and stable cash flow are also expected to benefit from the market's stabilization.AI can solve partial differential equations thousands of times faster than before, and partial differential equations play an important role in engineering and science. In a recent study, scientists from Johns Hopkins University in the United States have developed a new artificial intelligence (AI) model called "Differential Mapping Operator Learning" (DIMON), which can solve complex partial differential equations on personal computers, thousands of times faster than before, and is expected to "show its talents" in the fields of aerospace, automobiles and medicine. Related papers were published in the journal Nature Computational Science published on the 9th.